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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '220ae16407274099ac906a8c43050461c837686af0cc78627dd6b09a6b1c08d1' 
  AND token = 'JMj0nm9JzmEMe4F3v0IpG70fNVXUkz8FStKimBBQXMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}