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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8e27a849290d3b7bfd168fc288139f6d9143ed2509d0e6048303e4bfcf3fed6e' 
  AND token = 'HLzlwp6QbksCX2q9S1lsqwZ2aPcYLyOY7ljWOvQkxOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}