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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'aca2efbdd37097fc232204f4fee52613f0a3e6c013ba8b32ce8673b140f65c84' 
  AND token = 'QMUWrzkKCP+ePK4tFvGv9kGm0jfH1C7mUA8bGiOMBOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}