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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5f45008141620258d43515d7d0ead52e7fd36c28ba94f4490669d5d054c427f3' 
  AND token = 'lE7CiSqB1qNP2RrEJ+r8XjQIwbp1tau5Fr2/41jAbNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}