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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '212384c56c4913b5ad664a4dd3136cc001a7857eaba9485e63ead5eaf9218782' 
  AND token = 'CtOH8LAN2Fpt8GXfHR5HTsTsbksoHGRQokMKUG2mm5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}