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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b22e1ae44b4a4f1f4a7c2c87f74e1ecccaef3497c6e030470facee600e0df735' 
  AND token = 'a6VUvnX+KHrhgT1p1vVBZ/BGIsfp3l4O6cLTsthd7BA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}