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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e3d0318af73744f8e4e1a3f6f5b6eae73d1b8bf9b186c27780c6f71079883849' 
  AND token = 'TEabQ7ngIEYt91A0n+tMKkdPJrPn/4RYpl2oVOi2U8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}