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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2b2749e50f67e039d82dd56f1661b2e23bc49fa17b81d37d680bd1a66c527bea' 
  AND token = 'yTN3AanTV4E6tUIATaFke0NjUwJ6pgq0ihzsu69lPFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}