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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1e7302f56710ec085b136a451be2600943d336f2e7cc300589cf1616b34a32ce' 
  AND token = 'HOFDkA+x6o8xdIJ4fGzSEUCuXaVmPcAiIz1wTpeyeQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}