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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2494c4423f79f00a964a0567f7edd001a27eb3011071361215e5ba19f4e98cb8' 
  AND token = 'HIs0WhvbR23SEXdGKLQAsdXyBCSYt6iWKmtp2/aYn6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}