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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6a8e2ded1daa4f4325ddfcdd6fc12ac25d8acf0de1fcff77c65c241db9084488' 
  AND token = 'ihgLHfWX8DBualIkc6CgT8p4pSCbsj3SZ8wb5yfH2T0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}