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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'fde822e6630cf26ad60c50fba1dab1e3fd757c6595a7f3119e3e64b0859c8223' 
  AND token = 'tmzUHaK2QBXYHE3KT2v1HbsG0Mr3/C4bgF2NbHICR8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}