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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1cf788c37b598bc5bafda3a2933a117862a0444fdcc71408555f1d4c2390966e' 
  AND token = 'dmcTOKWnBn2AI7RS+HIamPndt+9141DpRQAj/rqXK3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}