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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd727da1eb279405d3b78e679c61c47f912d427e43db45184288c7773c184dd3d' 
  AND token = 'i1C5ewlwcaS6ER4HNbjpzcMTEFkDPvX+u4ERuul7fpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}