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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c09e2410fd514dd0b7c7870167b2ba020c473dde8a29b3bad1a00c65a22b4f07' 
  AND token = 'Fm448OgTHcWX1cnfSK9f2HCRBcq+B3wNeuR9kk6KQCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}