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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e2e7c2dbfc2550eed321db3a5c5b18614aa1514dad6a213955b11d4e006e35f6' 
  AND token = 'KhIarCIcS0mZLB4UFvr4LhL0ZDe8VHVQvW1phjMSlC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}