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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2de61550af81368287deb1a1002ccf5db1a8f71bda4af4d4b26d0aa65bbb690c' 
  AND token = 'QOvXns/gLiAW8I5QYagwwY4HtfWn66sqwL18ygIkSRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}