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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3a1ab480d292ce1a72a5325ac5897294138e80b87a23c63302b42e4908474012' 
  AND token = 'NXhkNKbnOWsQLXFqVlzlciR4fhKo5fYVqSbYXeqWDhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}