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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '209412e7ec30f33c590a3bd18bd0c2e9ded22fab90c9b77c287c2f7c3c628b91' 
  AND token = 'plAm2ZVRw+7fvcao/sbx1aByfAtwcgJxDVG/2SrQZxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}