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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '38b3c3253ae49f003edf1493a979b79fc1235867ff66325bb6016cef6d349706' 
  AND token = '/e2Rbw1xfTU3WHWav3sCKVEOAPi4pt7GPRfFiYkCxHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}