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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1d6b1da5394cd0afc0e70511c5226457a4565bfa41a88c5d3ad6dae0fa5454ed' 
  AND token = 'XXS+pokvka4jsVX+OkvlN7Wa/qFNyUGKBiHZU8MuX8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}