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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '431d3be8c409e01516a196ac2a20cac91f473fad2bf4e777c5593ba9dfcbc242' 
  AND token = '4Bm5BvkFrUruFsdofto8fYlqDj/iX46R9fN65oZkfMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}