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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a925cb5e731af3b589a2021fe4bc98a65e422f0ce4f751a3b4a70f30bd110262' 
  AND token = 'P173JBGYXbp2JNGo9e4v/Drzezgd1UqmoP96nW4pESM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}