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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '067779312e1cda871a51659d0c4f21a43e9f0e1f54e0dc178e240e32d5552645' 
  AND token = 'zl+P9rPIHJvtAIjuu4XXZDpPf+4TiZHiXrNlCeLjrVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}