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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a687461a709d9dbb04eb580f75c75745874e96c0fa666b38cc4f494696bf0204' 
  AND token = 'Yln7KhtEilsAF3EAu+TmA2IrT3xQwl/yT9ZCf1PwQvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}