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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e45e3fb8f3334db9b1fd29df4a9eb3c297bbaeb473f4bafd26d12e685bdab2f8' 
  AND token = 'S5GgwoZcIA3y14KD7wT4/+WJ0x9qxRHfqHhlS7yvrN8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}