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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e4f36c658c05cfb289219d275db4c6635996638e3c50fb083cff5d537d8eb079' 
  AND token = '7K3DbcBvcmstAlFjjXKcNsiV8MywfxM1G17ytXcvPsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}