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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b6a45afb26ccf6652ff21a2ff2efa06cfb57b61ac151234753d601a34af74205' 
  AND token = '60eTlHs2kKmmxDY2MOxEYyp+9zefhYFb8beEmRwecaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}