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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4f81465fadb7676043648f700f76598d8bc931aad5a3b9f13d80a6d4fee06996' 
  AND token = 'NjS38NxoF9Ua08Zh/Pfoo7giUA0O0/GNIFZnbPjf9s4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}