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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f44db33f7bd02eccb85b1b80deddaf780638d6a28c73e8a63764246ca4b5879d' 
  AND token = 'w+HZrcaxbRjMMm0T2jbSU/9S8t8/yz+gcf9H6cKskvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}