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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '45f9909230ac578dd805e024efe6401c197a2e38cec230c9b24af211392033e4' 
  AND token = '9BW590h9860vyAYghodi/El5N765gXVLOxuKsPCq7uQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}