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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '49a335392b296115a57d0509b1355ff0e47ca70ce3c47be72eff11e3557ead4a' 
  AND token = 'C1KZt1oOLe8l24v7rAWYbU8H8N6yIkpcOmwYE0LqHQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}