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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '42ac1d8a680887638696ffd8370ce141f5dfdc1d0e36401a948d75d6e051dc40' 
  AND token = 'cDyZzuDqb6wZCc+VxR3sAN8FKteLzQYaZjIIBaxxoTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}