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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '044d5dc73ed1def5c50c7be30994ee2300f09b04b14b4488d69c5bb9aaba02b8' 
  AND token = 'K3RgbB8sY5wmnlNcBGj1Wv/Ou7nVUEIE0VFI12n2DMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}