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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '41a93780d5fe20e9e7703b0394b8c6777984f22bbc215b7c5e7ca5a643142521' 
  AND token = 'aLmDidesR0IzRauW2LnlCJzmLLyQFlmRBwZjauDkfDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}