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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1e66b04d85a374bb017dea9686f8a49ee05217a122a1f70af617688810b61851' 
  AND token = 'FMNtMdHRKuIJmOAS0ibxUy6JzSWSgnYnJA8HyNikhls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}