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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '861d66e17999cc1de1353e8d4a8e21498cd66d868c7d1ae2da91c9d40e566532' 
  AND token = '0+fJDur/qv8Q5NSJvMcKjtAagLDQLKE8xQHB2waXiS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}