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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0e891ad55ac4cdc6da06f880114802e6e80ea30b0a45245121e0f5f0dd11ad60' 
  AND token = 'LxSUf2mEYzXp1WEKymPzmFAXiKtXzZuvUVJSDmutrAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}