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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '04cc44677a66c3bd46a9efad5c45313ffdead2afa6c4b8179f013c1d928e22d3' 
  AND token = '7SwtBq96krYJkSoz0ogad1jtAPx7aLaep3uONi+9+z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}