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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '292bba42c45f7f2f90d9661e1ce5945785aac830ad23ff9788c05883eb7cc8db' 
  AND token = 'Clv3DTzshp9K+E5CD0IZvf5fiyB9Fxzca2r29SgVN0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}