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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c6fc50ff4c544868f608f43e19b34c64782bfcd4b9ced27e2d74d15913b8e375' 
  AND token = '0O23JQHczpdJPh9264OY6HSGbjuvZokE7uAtz4V0pSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}