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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '305c9f0a4c82092b66fa406ce9bbc856770fa16a91b1a5c0a26e6fd3f18c5610' 
  AND token = 'F6XmdcLhREDehwdls3P6tFHdciKZmiXCUozCoPpmo1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}