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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8cd228386b4a471243e9fec4d70c527af9a52af64214141748af8a7a60d8368c' 
  AND token = 'vSI5JM+6AFhXFkPr76XGvZ39Z8jmey4+2l6sf5iX/+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}