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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '491bfa1c98b54267fb5d902ca0ef135bf62d6323c61ac02f905dd011d17b05f9' 
  AND token = 'HFs5ShRRkooCxPH8yNMhkB6CUgD+Rrvi4gqnOOKbUS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}