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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'fd21f9ef2b8258662ee7f27698d1e37e6559bfd529d6e967c6f6733382a78162' 
  AND token = '2vgP/W2050L7bvpnujnosNVhmlPSUasZdwkD1VUGaNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}