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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9e6801216620ef83d50ca3317aa45b1ba2268a06baa516b997cfec89438c4f1a' 
  AND token = 'pS7VzXMBWSc3a5p3Sk4TwFqEf989hE7FPwZFJ0OpdAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}