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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cbc6a68d00f806a057b2ef9bbad9f2c0979339580dade1213201e779f79b69f4' 
  AND token = 'qEqwfnT3GDI8ugJIFhlbY6zWeLo64WEvsoiONb5cLvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}