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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '43ac69954d57c9e44d3f2aaf37a1897d6162b23c309932feaeaa503589cc788e' 
  AND token = 'WIOcE8Idvmlanl6bNiuINXG/1E70xixeEvxTPUhw8vo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}