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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4ab928cc50056f3744fe8b86c19c1c9f5680553392fa5b817c65cd64f7454b8e' 
  AND token = 'h4N4n0wpkTF7bxf/pAYrUUK9plwcJ7nzUefOa8bTwqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}