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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '75834fef0e9bd39fd13c7027a45928afc1dec5c3085e5ecf377419eb1eec1ede' 
  AND token = 'lE76hw9KWmHpoV/ar0Z32E/cvd5LWos07TXxgbie7Xg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}